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Recent Issues
January 2012
Features
Pharmacotherapy for Post-traumatic Stress Disorder in Combat Veterans
Focus on Antidepressants and Atypical Antipsychotic Agents
Military clinical practice guidelines formerly recommended off-label atypical antipsychotic agents for treating traumatized war veterans. Although the guidelines have been revised, it may be too early to exclude these drugs in all cases.
Walter Alexander
News & Analysis
Pharmacy Groups Want to Change the FDA’s REMS Authority
Battles Loom as Congress Aims to Pass a Major Bill by September 2012
The REMS programs produced by drug companies vary greatly, often making life difficult for pharmacists, mainly because so far, the FDA has not established a standard format. The companies also haven’t been too happy with the FDA’s unfocused administration of its REMS authority, which the agency admits needs to be clarified.
Stephen Barlas
How Patient Cost-Sharing Trends Affect Adherence and Outcomes
A Literature Review
Reviewing articles and abstracts published from January 1974 to May 2008, the authors found that increasing patient cost sharing was associated with declines in medication adherence, which in turn were related to poorer health outcomes.
Michael T. Eaddy, PharmD, PhD; Christopher L. Cook, PharmD, PhD; Ken O’Day, PhD, MPA; Steven P. Burch, PhD, RPh; and C. Ron Cantrell, PhD
Meeting Highlights
American Heart Association Scientific Sessions 2011
Topics include extended-release niacin for lowering low-density lipoprotein-
cholesterol; vorapaxar for reducing acute coronary syndromes; the use of drug-eluting stents instead of balloon-eluting stents in patients at risk for bleeding; and the impact of free drugs versus copays on adherence to medications.
Walter Alexander
Departments
Medication Errors
Some Red Rules Shouldn't Rule in Hospitals
Matthew Grissinger, RPh, FASCP
Prescription: Washington
Medicare Wants Only ‘Independent’ Consultant Pharmacists in Nursing Homes
Medicare wants to make sure that consultant pharmacists who work in long-term-care facilities have no conflicts of interest.
Stephen Barlas
New Drugs/Drug News/New Medical Devices
FDA approvals, drug indications, and updates
Pharmaceutical Approval Update
Ruxolitinib (Jakafi) for the treatment of myelofibrosis, aflibercept (Eylea) for patients with neovascular (wet) age-related macular degeneration; and cord blood (Hemacord) for stem-cell transplantation
Marvin M. Goldenberg, PhD, RPh, MS
Drug Forecast
Vilazodone HCl (Viibryd)
A Serotonin Partial Agonist and Reuptake Inhibitor for the Treatment of Major Depressive Disorder
Vilazodone (Viibryd) for major depressive disorder
Martin Paspe Cruz, PharmD, CGP, BCPP
